The event includes a business roundtable, a luncheon and a photo opportunity with the senator.
A handful of other potential 2016 presidential candidates — Sen. Ted Cruz (R-Texas) and Rand Paul (R-Ky.) — have also pledged to help the Republican in the final leg of his campaign. He's lagged Democrat Terry McAuliffe in recent polls of the race.
Two other governors, Louisiana's Bobby Jindal (R) and Wisconsin's Scott Walker (R) have already visited Virginia to campaign for Cuccinelli.
Those visits to the swing state offer possible presidential contenders the opportunity to build goodwill among the state's activists and operatives.
Rubio headlining September fundraiser for Va. GOP gubernatorial candidate
Tickets for the Sept. 16 fundraiser, which will be held at the Marriott hotel in Richmond, Va., range from $50 to $25,000.