Rep. Bob Inglis (R-S.C.) became the third House member to lose a primary this cycle, suffering a resounding defeat in Tuesday's runoff against Spartanburg prosecutor Trey Gowdy (R).
With 177 of 265 precincts reporting, Gowdy had 72 percent of the vote. Inglis took 28.
The Associated Press called the race for Gowdy.
Inglis also came in second in the June 8th election with 27 percent of the vote, trailing Gowdy by almost 12 points.
Inglis closed the final days of the runoff election by touting his experience, an argument that has been met with mixed results as an anti-incumbent mood roils the country.
The six-term lawmaker also rolled out the endorsement of Bob Jones III, the chancellor of Bob Jones University, which is in his district. Jones, however, was unavailable to appear for Inglis because he was traveling.
Gowdy, meanwhile, launched a 30-second TV ad that touted his conservative principles. He also has the support of Bob Taylor, a Greenville County councilman and dean of the College of Arts and Science at Bob Jones University.
Inglis represents one of the most conservative districts in the country. But he angered his constituents by voting for the Wall Street bailout and with the Democrats on a resolution condemning the Iraq war surge. He's also expressed concern about global warming, which prompted one of his previous opponents to dub him the "Al Gore of the Republican Party."
Perhaps the last straw for some of his critics came when he told constituents at a forum on healthcare to "turn Glenn Beck off."