Former Air Force pilot Martha McSally (R) narrowly leads Rep. Ron Barber (D-Ariz.).
Fitzpatrick, long a proponent of term limits, announced in his victory speech on Thursday that this will be his last term in Congress.
In several races, the truism that candidates matter still held true.
Rep. Scott Peters led Carl DeMaio, a gay Republican, in one of most competitive races.
"We came up a little short," Khanna said in a statement Friday.
“When Louisiana needed disaster aid, I was there. Where was Bill?” said Sen. Landrieu.
Honda leads fellow Dem Ro Khanna 52-48, but the race has not been called.
A winner has yet to be declared in nine House races three days after Election Day.
Rep. Steve Israel (D-N.Y.) attributed part of the challenge to “top of the ticket drag."
Indicted Rep. Michael Grimm (R-N.Y.) is fresh off a decisive reelection win.