Sylvia Mathews Burwell sailed through Senate confirmation to be the next secretary of Health and Human Services on Thursday — but all three of the Republican senators eyeing a White House bid voted against her.

Sens. Ted CruzRafael (Ted) Edward CruzTexas Republicans slam White House over disaster relief request Dem rep: Trump disaster aid request is 'how you let America down again' Moore endorsements disappear from campaign website MORE (Texas), Rand PaulRandal (Rand) Howard PaulCongress must end American support for Saudi war in Yemen Black men get longer prison sentences than white men for same crimes: study Sarah Palin on sexual harassment: 'People know I'm probably packing' so they 'don't mess with me' MORE (Ky.) and Marco RubioMarco Antonio RubioCongress faces growing health care crisis in Puerto Rico The Hill's 12:30 Report Colbert mocks Trump for sipping water during speech on Asia trip MORE (Fla.) were three of just 17 senators to vote against confirming Burwell, while more than 20 other Republicans backed her. This is the latest time they’ve joined the right flank of the Senate to buck bipartisan legislation or confirmations.

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The trio have long been keeping an eye on one another, making sure they don’t give anyone a chance to hit them from the right in a GOP primary (with Rubio’s immigration push being the glaring exception). And while Burwell’s nomination is unlikely to become a major campaign issue two years from now, it’s the latest sign they may struggle to move back to the center should any of them win the GOP nomination.

 

SENATE SHOWDOWN

MS-SEN (COCHRAN): State Sen. Chris McDaniel got off to a rocky start in the runoff contest with Sen. Thad CochranWilliam (Thad) Thad CochranTrump asks for another billion in disaster aid Congressional leaders eyeing two-year caps deal up to 0 billion Senate passes resolution requiring mandatory sexual harassment training MORE (R-Miss.), struggling to explain why a staffer and two supporters his campaign sent to a county courthouse long after ballot counting was over Tuesday night ended up locked in the courthouse for more than an hour. The Hinds County Sheriff’s Office investigated the matter and found that none of the individuals had engaged in any criminal activity, but it gave Cochran’s team fodder for attacks, with spokesman Jordan Russell declaring the McDaniel campaign “full of criminals.”

Meanwhile, National Republican Senatorial Committee Chairman Jerry MoranGerald (Jerry) MoranOvernight Cybersecurity: Kushner was contacted about WikiLeaks before election | Tech experts blast Trump's 'extreme vetting' plan | Senate passes defense bill with measure to modernize feds' IT Ensuring that defense agencies will have access to a community of entrepreneurs and innovators Provision to modernize federal IT in compromise defense bill MORE (Kan.) said Thursday it's a "much clearer race" for Republicans if Cochran wins, but that the committee would ultimately back McDaniel if he wins.

LA-SEN (LANDRIEU): In his first ad of the Louisiana Senate race, Rep. Bill Cassidy (R-La.) addresses the camera wearing his doctor’s coat while holding a copy of the Affordable Care Act, decrying lawmakers who supported it without reading it and touting his opposition to the law.

AK-SEN (BEGICH): Alaska Senate candidate Dan Sullivan (R) fires back at Sen. Mark BegichMark Peter BegichPerez creates advisory team for DNC transition The future of the Arctic 2016’s battle for the Senate: A shifting map MORE (D-Alaska) in a new ad, responding to Begich making fun of him for filming an ad on a building that Begich helped secure funding to build.

“It must be election time. Mark Begich is pretending to ride snow machines, and taking credit for other people’s work,” he says in the spot. “Now, he’s even giving me advice on political ads! I’m not a career politician like Mark, but I thought I’d return the favor. Mark, in your next ad, tell us why you vote with Barack ObamaBarack Hussein ObamaReport: FCC chair to push for complete repeal of net neutrality Right way and wrong way Keystone XL pipeline clears major hurdle despite recent leak MORE 97 percent of the time.”

KY-SEN (MCCONNELL): Democrat Alison Lundergan Grimes drew ridicule from Republicans for using a stock photo of a European male model posing as a coal miner in a campaign ad hitting President Obama for his energy policies. Her campaign said the version of the ad circulated to reporters last week was not the final version, and that they swapped out the European model for a photo shot by an American photographer.

VA-SEN (WARNER): Former Republican National Committee Chairman Ed Gillespie (R) outlined his economic plan in a conference call just days before he’s expected to win the nomination at the GOP’s state convention on Saturday, hitting Sen. Mark WarnerMark Robert WarnerTech beefs up lobbying amid Russia scrutiny Overnight Tech: Senate Dems want FCC chief recused from Sinclair merger | Tech rallies on Capitol Hill for DACA | Facebook beefs up lobbying ranks Facebook adds two lobbyists amid Russia probe MORE (D-Va.) on energy production and ObamaCare. Gillespie dodged when asked whether he believes that global warming is being caused by human activity. 

OK-SEN (OPEN): Rep. Darrell Issa (R-Calif.) will appear at a campaign event with Rep. James Lankford (R-Okla.) this weekend, but a Lankford staffer said the appearance doesn’t amount to an endorsement. Lankford is battling former Oklahoma Speaker T.W. Shannon for the GOP nomination to replace retiring Sen. Tom CoburnTom CoburnFormer GOP senator: Trump has a personality disorder Lobbying World -trillion debt puts US fiscal house on very shaky ground MORE (R-Okla.).

MI-SEN (OPEN): Rep. Gary Peters (D-Mich.) is out with a Web video parodying Seinfeld to say Terri Lynn Land (R)’s campaign is about “nothing.”

IA-SEN (OPEN): Iowa state Sen. Joni Ernst’s (R) campaign is crying “fowl,” claiming Rep. Bruce BraleyBruce BraleyOPINION | Tax reform, not Trump-McConnell feuds, will make 2018 a win for GOP Ten years later, House Dems reunite and look forward Trump: Ernst wanted 'more seasoning' before entertaining VP offer MORE’s (D-Iowa) new ad portraying her as a baby bird is "degrading women by comparing Joni Ernst to a 'chick' in his latest campaign ad" in a complaint echoed by some national GOP strategists. The ad never uses the word chick.

 

BATTLE FOR THE HOUSE

WV-03 (RAHALL): A new poll conducted by a Democratic pollster for House Majority PAC, which is backing Rep. Nick RahallNick RahallLikely W.Va. Senate GOP rivals spar in radio appearances West Virginia is no longer Clinton country Solution needed: Rail congestion is stifling economic growth MORE (D), shows him leading his Republican challenger Evan Jenkins, 52-39 — about the same as an April poll from the same group.

MI-3 (AMASH): Reps. Mike Rogers (R-Mich.) and Devin Nunes (R-Calif.) are headlining a fundraiser for Rep. Justin AmashJustin AmashThe 13 House Republicans who voted against the GOP tax plan House Judiciary advances warrantless wiretapping reform bill The Hill's Whip List: Where Republicans stand on tax-reform bill MORE’s (R-Mich.) primary opponent, businessman Brian Ellis (R). Both have long been harshly critical of the libertarian-leaning Amash on foreign policy.

CA-33 (OPEN): Retiring Rep. Henry Waxman (D-Calif.) endorsed California state Sen. Ted Lieu (D) for his seat, the day after Lieu and a long-shot Republican advanced in the primary.

MN-8 (NOLAN): Republican Stewart Mills rolled out his first ad, a spot saying he learned at his family hunting camp that you shouldn’t complain about things, you should fix them, and that he wants to go “fix” Washington.

 

2016 WATCH

CLINTON: Hillary ClintonHillary Diane Rodham ClintonO’Malley tells Dems not to fear Trump FBI informant gathered years of evidence on Russian push for US nuclear fuel deals, including Uranium One, memos show Pelosi blasts California Republicans for supporting tax bill MORE, asked about her vote for the Iraq War, said “I still got it wrong. Plain and simple." The vote continues to dog her with some liberals.

She also said she continues to take blood thinners after doctors found a blood clot between her brain and skull in 2012. But she told People magazine she has no lingering effects from a concussion that she suffered shortly before the clot was discovered.

 

QUOTE OF THE DAY

“I haven’t received any response from people here because, as you know, no one knows who the hell I am.” — Thomas Carey, the third Republican candidate for Senate in Mississippi who drew 2 percent support in the primary Tuesday night, pushing the race to a runoff