Republicans are needling Hillary ClintonHillary Rodham ClintonTrump in campaign form at NRA convention Vicente Fox to Trump: ‘Being president ain’t easy’ When political opportunity knocked, Jason Chaffetz never failed to cash in MORE after she lost the New Hampshire Democratic primary to Bernie SandersBernie SandersNRA head: Sanders 'a political predator' What would Bernie say to Wall Street for 0K? Sanders warns of possible nuclear war with North Korea MORE, her first defeat of the contest.
"No amount of spin can make up for such a crushing defeat in a state that has for decades been in the Clintons’ corner," said Republican National Committee Chairman Reince Priebus in a statement.
"The prospect that Democrats could nominate a self-avowed socialist is growing more probable by the day, and shows how off course Hillary Clinton’s coronation has gone," he added.
Multiple news outlets quickly declared that Sanders had won the Granite State primary shortly after polls closed at 8 p.m. on Tuesday.
Clinton's campaign had a concession prepared, which they released immediately. The memo said they were turning their focus to South Carolina and Nevada.
Sanders was widely expected to win Tuesday's contest in what has become a tougher-than-expected Democratic primary for Clinton. But Clinton's allies point to her strong leads in the next two states voting, where she has an edge with minority voters.
On the Republican side, outspoken billionaire Donald TrumpDonald TrumpWHCA dinner could be Trump's chance to one-up the media. He should take it. Trump promises border wall still coming at NRA summit Perez: Trump and Republican in Georgia runoff are '2 peas in a pod' MORE was easily declared the winner of the New Hampshire primary, though the battle for second and third place has yet to be declared.
Democratic National Committee Chairwoman Debbie Wasserman Schultz (D-Fla.) congratulated Sanders for his win and also praised Clinton.
She also hit out at GOP winner Trump.
"Donald Trump started his campaign calling immigrants rapists and drug dealers, eventually called for banning members of an entire religion from entering America and recently said he would bring back interrogation techniques ‘a hell of a lot worse than waterboarding,'" the Florida representative said in a statement.
“Trump’s dominance over the Republican Party is a troubling development in our politics, but it also means the choice this November will be crystal clear."