White House hopeful Marco RubioMarco RubioMexican politicians have a new piñata: Donald Trump Bush ethics lawyer: Congress must tell Trump not to fire Mueller The private alternative to the National Flood Insurance Program  MORE ripped rival Ted CruzTed CruzGOP wrestles with soaring deductibles in healthcare bill Cruz: Tax reform chances ‘drop significantly’ if healthcare fails Ex-CBO directors defend against GOP attacks on ObamaCare analysis MORE at Saturday's presidential debate for a "pattern" of telling lies, particularly about immigration reform.

"This is a disturbing pattern now. For a number of weeks Ted Cruz has just been telling lies," Rubio said. "He's lying about all sorts of things and now he's just making things up." 

The Florida senator said that Cruz had lied "about Ben Carson in Iowa," referring to the Carson campaign's accusations that Cruz's campaign spread false rumors during the caucuses that the retired neurosurgeon was dropping out of the presidental race. 
Rubio's comments came as he and the Texas Republican battled over their stance in a 2013 fight in the Senate over a wide-ranging immigration reform bill. 
Cruz has repeatedly knocked Rubio for working with Democrats, calling the "Gang of Eight" bill the "Rubio-Schumer amnesty plan," referring to Sen. Charles SchumerCharles SchumerTrump: Why aren't 'beleaguered AG,' investigators looking at Hillary Clinton? Trump: Washington ‘actually much worse than anyone ever thought’ Schumer: Dems didn't 'tell people what we stood for' in 2016 MORE (D-N.Y.), who is expected to be the next Democratic leader. 
"The question for anyone on illegal immigration, is where were you in that fight," Cruz added. 
Rubio, however, has pointed to amendments that the Texas senator pushed that removed a path to citizenship from the bill but kept work permits.
Asked about his tactics on the Senate's immigration bill, which ultimately stalled in the House, Cruz has said that the amendments were meant to expose Democrats' "bluff" and ultimately undermine the Gang of Eight bill.
Rubio wasn't alone at the South Carolina event in accusing Cruz of lying. Donald TrumpDonald TrumpOPINION | With Scaramucci at the mic, Trump has a chance to take on a hostile press Feehery: Winning August Press: Amateur hour at White House MORE also said Cruz "is the single biggest liar. ...This guy will say anything."