White House hopeful Marco RubioMarco Antonio RubioDem scores upset over Republican in Florida county commissioner race GOP senators introduce bill to prevent family separations at border McCain, Coons: Trump should withdraw controversial refugee nominee MORE ripped rival Ted CruzRafael (Ted) Edward CruzConservatives express concern over House GOP immigration bill GOP senators introduce bill to prevent family separations at border Senate GOP tries to defuse Trump border crisis MORE at Saturday's presidential debate for a "pattern" of telling lies, particularly about immigration reform.

"This is a disturbing pattern now. For a number of weeks Ted Cruz has just been telling lies," Rubio said. "He's lying about all sorts of things and now he's just making things up." 

The Florida senator said that Cruz had lied "about Ben Carson in Iowa," referring to the Carson campaign's accusations that Cruz's campaign spread false rumors during the caucuses that the retired neurosurgeon was dropping out of the presidental race. 
Rubio's comments came as he and the Texas Republican battled over their stance in a 2013 fight in the Senate over a wide-ranging immigration reform bill. 
"The question for anyone on illegal immigration, is where were you in that fight," Cruz added. 
Rubio, however, has pointed to amendments that the Texas senator pushed that removed a path to citizenship from the bill but kept work permits.
Asked about his tactics on the Senate's immigration bill, which ultimately stalled in the House, Cruz has said that the amendments were meant to expose Democrats' "bluff" and ultimately undermine the Gang of Eight bill.
Rubio wasn't alone at the South Carolina event in accusing Cruz of lying. Donald TrumpDonald John TrumpConservatives express concern over House GOP immigration bill Poll: McSally holds 14-point lead in Arizona GOP Senate primary Trump defends Nielsen amid criticism over family separations MORE also said Cruz "is the single biggest liar. ...This guy will say anything."