Republican presidential candidate Donald TrumpDonald John TrumpIG investigating Comey memos over classified information: report Overnight Defense: Congress poised for busy week on nominations, defense bill | Trump to deliver Naval Academy commencement speech | Trump administration appeals decision to block suspected combatant's transfer Top Pruitt aid requested backdate to resignation letter: report MORE on Tuesday accused rival Ted CruzRafael (Ted) Edward CruzCruz's Dem challenger slams Time piece praising Trump Race for Republican Speaker rare chance to unify party for election 32 male senators back Senate women's calls to change harassment rules MORE of having “a mental problem.”

“Seriously, he’s got a mental problem,” Trump told host Maria Bartiromo on Fox Business Network’s "Mornings with Maria."

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“There’s never been any politician — or almost anybody in my life — that I’ve seen that lies so much.”

Trump said Cruz is misleading Americans about Trump's fundamental policy positions on hot-button topics including gun control and healthcare.

“He will say I’m against the Second Amendment,” he said. “He will say I’m terribly in favor of ObamaCare, which is ridiculous. These are things that are staples of what I'm about.

"I’m totally in favor of the Second Amendment. ... I want the Second Amendment — I’d strengthen it if anything."

Trump added that other GOP White House hopefuls have slammed Cruz for dishonesty.

“By the way, I’m not the only that said it,” he said. "Marco RubioMarco Antonio RubioStudents gather outside White House after walkout to protest gun violence Overnight Energy: Senate confirms Bridenstine as NASA chief | Watchdog probes Pruitt’s use of security detail | Emails shine light on EPA science policy changes Senate confirms Trump’s pick to lead NASA MORE called him a liar during the debate.”

Cruz has repeatedly accused Trump and Rubio of not being sufficiently conservative. He accused both men on Monday of shouting “liar” at critics anytime their actual beliefs are put in the spotlight.

“It is not being honest or candid for either Marco Rubio or Donald Trump to pretend that their records are different than what they are and simply yell and scream at anyone who points to the words that have come out of their own mouths,” Cruz said.