Republican presidential hopeful Jeb Bush on Saturday sneezed at the notion of serving as the running mate to primary front-runner Donald TrumpDonald TrumpCarter Page questioned in FBI Russia investigation: report Major progressive group rolls out first incumbent House endorsement Amazon’s acquisition of Whole Foods underscores the threat posed by ‘big data’ MORE.

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“No,” he responded sharply to a reporter in South Carolina, drawing laughs. “Let’s be clear: I don’t think he would ask me.”

Former Republican primary candidate Sen. Lindsey GrahamLindsey GrahamNew CBO analysis imperils GOP ObamaCare repeal Senate panel questions Lynch on alleged FBI interference The Hill's Whip List: Senate ObamaCare repeal bill MORE (R-S.C.), who has endorsed Bush for president, can be seen chuckling at the suggestion, as well.

The former Florida governor has repeatedly questioned Trump’s conservatism and balked at the billionaire businessman’s abrasive manner.

Trump, for his part, has needled Bush as a “low-energy” candidate and accused his brother, former President George W. Bush, of lying about the Iraq invasion.