Marco RubioMarco Antonio RubioOvernight Cybersecurity: Bipartisan bill aims to deter election interference | Russian hackers target Senate | House Intel panel subpoenas Bannon | DHS giving 'active defense' cyber tools to private sector Senators unveil bipartisan push to deter future election interference Puerto Rico's children need recovery funds MORE ridiculed Donald TrumpDonald John TrumpDems flip Wisconsin state Senate seat Sessions: 'We should be like Canada' in how we take in immigrants GOP rep: 'Sheet metal and garbage' everywhere in Haiti MORE's approach to finding Middle East peace, saying that Israeli-Palestinian talks are not like a real estate deal.

"The Palestinians are not a real estate deal, Donald," the White House contender said in Thursday night's CNN Republican debate in Houston.

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Rubio and Ted CruzRafael (Ted) Edward CruzWith religious liberty memo, Trump made America free to be faithful again Interstate compacts aren't the right way to fix occupational licensing laws Texas Dem: ‘I don’t know what to believe’ about what Trump wants for wall MORE both hit the billionaire businessman for saying that he would be a neutral broker in peace negotiations between the Israelis and the Palestinians.

Both Rubio and Cruz say they would stand unequivocally with Israel, while the party front-runner argues that neutrality is required to make what would be "probably the toughest deal of any kind."

"A deal is a deal," Trump replied, when Rubio made the point that Middle East peace talks had nothing to do with negotiating real estate.

Rubio hit back: "A deal is not a deal when you're dealing with terrorists. Have you ever negotiated with terrorists?"

Trump, who was under attack from the Florida senator all night, replied, "You are not a negotiator. And with your thinking you will never bring peace."

"Donald might be able to build condos in the Palestinian areas, but ... this is not a real estate deal," Rubio said to close the exchange.