Donald TrumpDonald TrumpWhy Americans should be bitter over Trump’s sweetened Mexican sugar deal Dems push leaders to talk less about Russia Kobach fined over Trump meeting memo MORE returned Marco RubioMarco RubioWill Republicans stand up to the NRA's insurrection rhetoric? The Hill's Whip List: Senate ObamaCare repeal bill Ivanka Trump turns to House GOP on paid family leave MORE’s fire Friday, calling his presidential rival inexperienced and a “nervous Nellie” at a press conference and rally. 

Responding to a morning campaign rally where Rubio questioned whether the business mogul wet himself during their argument in Thursday night's GOP debate, Trump cut Rubio down. 

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“I watched a part of his little act and he’s a desperate guy. ... He is not presidential material, I can tell you. He doesn’t have the demeanor, he’s a nervous Nellie," Trump said during a Friday press conference. 

Pushing back on the Florida senator's characterization that Trump threw a temper tantrum backstage, the GOP front-runner called Rubio a "total mess" backstage during that debate and said he was "putting on makeup with a trowel."

At one point during the speech, Trump held up a water bottle and said, “It’s Rubio,” before throwing water over the stage and tossing the water bottle — an apparent swipe at Rubio’s on-stage water breaks during the debate.

And he slapped at his competitor's lackluster Senate attendance as well as recent polls that put him up big over him.

"For me to go into Florida and have a 20-point lead over the sitting senator, the sitting senator abandoned Florida," Trump said. 

“They elected him as a young senator and before he sits down, he starts running for president."

Chris Christie, who endorsed Trump during that Friday press conference and introduced him at the subsequent rally, drove the knife in further.

"President of the United States is not a no-show job like you treated the United States Senate," he said to Rubio. 

Trump went on to repeat those barbs against Rubio during the rally, going on at length with criticisms of Rubio from the trail, lauding Christie for attacking Rubio during a February debate before the New Jersey governor dropped out of the presidential race.

"I watched Chris take a man apart and I looked at him, honestly, I thought he was going to die," Trump said. 

"He was so scared, like a little frightened puppy." 

 Harper Neidig contributed