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CPAC has long been a stopping point for GOP presidential aspirants. Rubio, who has spoken at previous CPACs in previous years, is seen as a likely contender for the nomination.

"My friend Marco RubioMarco RubioThe Memo: Searching for firm footing as Trump Era begins Overnight Energy: Senate panel clears Tillerson for State Senate panel votes to confirm Tillerson MORE has quickly become one of our nation's most prominent conservative leaders," American Conservative Union Chairman Al Cardenas said in the release announcing the news. "Sen. Rubio's participation will serve as motivation to CPAC attendees and conservatives across the country to take action and bring our country back on track."

Rep. Paul RyanPaul RyanSanders set for clash with Trump’s budget pick Is healthcare law really going into a ‘death spiral’? Trump hosts Hill leaders for ice breaker MORE (R-Wis.) is already scheduled to speak at the event, as is former Sen. Rick Santorum (R-Pa.).

The three-day event, in its 40th year, will be held in mid-March.