"Look, I think I got to be a part of the most special campaign, two campaigns, in our lifetime. And, we’ll see," he said on a "Meet the Press" PRESS Pass interview in response to a question about his future in politics.
Messina served as Obama's deputy chief of staff after joining his successful 2008 bid, and ran his reelection campaign. He now chairs the nonprofit backing Obama's agenda, Organizing for America.
If Vice President Biden decides to run in 2016, Messina could play a role in his campaign. The two, according to an early report, have a strong relationship after working together in the White House.
For now, however, Messina is heading up OFA, which has come under fire for, critics say, acting inappropriately as a political arm for the president and taking donations from special interests.
While Messina said that there's "absolutely" too much money in politics, he pushed back against critics, saying that the nonprofit is supported by small donations and grassroots supporters.
"This organization is funded and fueled by grassroots people across the country. The average contribution to the campaign was 51 dollars, and that’s about what we’re seeing of OFA," he said.
OFA has so far launched ads targeting GOP lawmakers who oppose background checks, which drew the ire of some of those Republicans, who suggested it might poison the well.
But Messina said that the organization was willing to work across the aisle on certain issues.
"Well, OFA is a nonpartisan organization, it’s going to work with members of both parties, to advocate for the president’s legislative agenda. It’s not political," he said.
A spokesperson for the group declined to elaborate on what issues OFA would engage in.