Howard Dean doubled down Tuesday on his insinuation that Donald TrumpDonald John TrumpReporters defend CNN's Acosta after White House says he 'disrespected' Trump with question Security costs of Trump visit to Scotland sparks outrage among Scottish citizens Ex-CIA officer: Prosecution of Russians indicted for DNC hack 'ain't ever going to happen' MORE's debate-night sniffles were related to cocaine use.

"That is actually a signature of people who use cocaine," Dean said on MSNBC.

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"I'm not suggesting that Trump does, but I'm suggesting we think about it, because here's the interesting constellation — he sniffs during the presentation, which is something that users do. He also has grandiosity, which is something that accompanies that problem. ... It's something I think it'd be interesting to ask him and see if he ever had a problem with that."

There is no evidence that Trump, the Republican presidential nominee, has ever used cocaine. The businessman has long said he doesn’t drink alcohol or take any illegal drugs.

Dean, a doctor and former chairman of the Democratic National Committee, first raised the cocaine allegation in a tweet on Monday night as social media exploded with commentary about Trump’s breathing, which was picked up by his microphone.

"Notice Trump sniffling all the time. Coke user?" Dean tweeted

MSNBC's Kate Snow pushed back on Dean's assertions, questioning how they were different from unfounded innuendo about Democratic presidential nominee Hillary ClintonHillary Diane Rodham ClintonDHS secretary: No sign Russia targeting midterm elections at 2016 level Twitter suspends Guccifer 2.0 and DCLeaks accounts after indictments Elon Musk donated nearly K to Republican PAC, filings show MORE's health from Trump's orbit. Dean countered by criticizing Trump for not releasing "meaningful" health records.

"I raised the question last night," Dean said. 

"But I don't think this is a ridiculous idea. Something funny was going on with Trump last night. Do I think it's cocaine, probably not. But again, the sniffling, the grandiosity, the delusions, the pressured speech — this guy has already proven himself to be unstable, the question is: Why is he unstable?

"Do I think he has a cocaine habit? I think it's unlikely that you could mount a presidential campaign at 70 years old with a cocaine habit, but it was pretty striking."