Sen. Patty MurrayPatricia (Patty) Lynn MurrayOvernight Health Care — Sponsored by PCMA — Trump official won't OK lifetime limits on Medicaid Dems warn against changes to federal family planning program Overnight Health Care: Drug company under scrutiny for Michael Cohen payments | New Ebola outbreak | FDA addresses EpiPen shortage MORE (D-Wash.) will take the helm of the Democratic Senatorial Campaign Committee in 2012, according to a Democrat with knowledge of the decision.

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Murray previously headed the DSCC in 2002, a year that saw Republicans net two Senate seats. 

Facing the prospect of defending more than 20 Democratic seats in 2012, Senate Majority Leader Harry ReidHarry Mason ReidMcConnell not yet ready to change rules for Trump nominees The Hill's Morning Report — Sponsored by CVS Health — Trump’s love-hate relationship with the Senate Trump to press GOP on changing Senate rules MORE (D-Nev.) has struggled to find a replacement for Sen. Bob MenendezRobert (Bob) MenendezThe Hill's Morning Report: Can Trump close the deal with North Korea? Senate must save itself by confirming Mike Pompeo Poll: Menendez has 17-point lead over GOP challenger MORE (D-N.J.), whose own seat is up in 2012.

Reid reportedly asked Sen. Chuck SchumerCharles (Chuck) Ellis SchumerThe Hill's 12:30 Report — Sponsored by Delta Air Lines — GOP centrists in striking distance of immigration vote Schumer: Trump should take Kim Jong Un off 'trip coin' Overnight Finance: Trump signs repeal of auto-loan policy | Justices uphold contracts that bar employee class-action suits | US, China trade war 'on hold' MORE (D-N.Y.), who headed the committe in 2006 and 2008, to take the helm for a third time but Schumer declined. Reid also approached a number of other senators about the job, including Sens. Michael BennetMichael Farrand BennetGOP, Dem lawmakers come together for McCain documentary Overnight Health Care — Sponsored by PCMA — Trump official won't OK lifetime limits on Medicaid Hillicon Valley: White House eliminates top cyber post | Trump order looks to bolster agency CIOs | Facebook sees spike in violent content | Senators push NIH on tech addiction | House to get election security briefing MORE (D-Colo.) and Mark WarnerMark Robert WarnerConservatives leery of FBI deal on informant Overnight Finance: House sends Dodd-Frank rollbacks to Trump | What's in the bill | Trump says there is 'no deal' to help ZTE | Panel approves bill to toughen foreign investment reviews DHS secretary says she hasn’t seen assessment that Russia interfered to help Trump win MORE (D-Va.), but they too declined.

Murray just won her own difficult reelection bid.

Republicans are bullish on taking back the Senate majority in 2012 after capturing six seats this fall. High of the list of GOP targets in two years are Sens. Ben Nelson (D-Neb.), Claire McCaskillClaire Conner McCaskillThe Hill's Morning Report — Sponsored by PhRMA — Republicans see some daylight in midterm polling Trump urges anti-abortion advocates to rally in November Calif. gov candidates battle for second place MORE (D-Mo.), Jim Webb (D-Va.) and Joe ManchinJoseph (Joe) ManchinOvernight Finance: House sends Dodd-Frank rollbacks to Trump | What's in the bill | Trump says there is 'no deal' to help ZTE | Panel approves bill to toughen foreign investment reviews House votes to ease regulation of banks, sending bill to Trump Senators demand answers on Trump’s ZTE deal MORE (D-W.Va.).

-- This post was updated at 12:31 p.m.