Sen. Patty MurrayPatty MurrayCBO to release report Tuesday on ending ObamaCare insurer payments OPINION | Progressives, now's your chance to secure healthcare for all McConnell open to bipartisan deal on health insurance payments MORE (D-Wash.) will take the helm of the Democratic Senatorial Campaign Committee in 2012, according to a Democrat with knowledge of the decision.

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Murray previously headed the DSCC in 2002, a year that saw Republicans net two Senate seats. 

Facing the prospect of defending more than 20 Democratic seats in 2012, Senate Majority Leader Harry ReidHarry ReidOPINION | 5 ways Democrats can win back power in the states THE MEMO: Trump's base cheers attacks on McConnell It's time for McConnell to fight with Trump instead of against him MORE (D-Nev.) has struggled to find a replacement for Sen. Robert MenendezRobert (Bob) MenendezLawmakers target horse meat trade Senators, staff get approval to testify in Menendez corruption trial Trump admin not opposed to new war authorization MORE (D-N.J.), whose own seat is up in 2012.

Reid reportedly asked Sen. Chuck SchumerCharles SchumerDemocrats urge Trump to condemn Charlottesville violence Melania Trump on Charlottesville protests: 'No good comes from violence' It's time for McConnell to fight with Trump instead of against him MORE (D-N.Y.), who headed the committe in 2006 and 2008, to take the helm for a third time but Schumer declined. Reid also approached a number of other senators about the job, including Sens. Michael BennetMichael Farrand BennetNFL player points to Charlottesville after national anthem protest Trump quietly putting his stamp on the courts Overnight Energy: Senate begins moving energy nominations | Interior watchdog probing Zinke calls MORE (D-Colo.) and Mark WarnerMark WarnerTrump declares 'racism is evil' after firestorm How the New South became a swing region How to fix Fannie and Freddie to give Americans affordable housing MORE (D-Va.), but they too declined.

Murray just won her own difficult reelection bid.

Republicans are bullish on taking back the Senate majority in 2012 after capturing six seats this fall. High of the list of GOP targets in two years are Sens. Ben Nelson (D-Neb.), Claire McCaskillClaire McCaskillSenators push for possible FCC enforcement over Lifeline fraud Democrat senator: Trump has elevated Kim Jong-Un to the world stage It's time for McConnell to fight with Trump instead of against him MORE (D-Mo.), Jim Webb (D-Va.) and Joe ManchinJoe ManchinOPINION | 5 ways Democrats can win back power in the states Trump's Democratic tax dilemma Manchin eyed as potential pick for Energy secretary: report MORE (D-W.Va.).

-- This post was updated at 12:31 p.m.