Sen. Patty MurrayPatricia (Patty) Lynn MurrayChildren’s health-care bill faces new obstacles Overnight Health Care: Schumer calls for tying ObamaCare fix to children's health insurance | Puerto Rico's water woes worsen | Dems plead for nursing home residents' right to sue Schumer calls for attaching ObamaCare fix to children's health insurance MORE (D-Wash.) will take the helm of the Democratic Senatorial Campaign Committee in 2012, according to a Democrat with knowledge of the decision.

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Murray previously headed the DSCC in 2002, a year that saw Republicans net two Senate seats. 

Facing the prospect of defending more than 20 Democratic seats in 2012, Senate Majority Leader Harry ReidHarry ReidChris Murphy’s profile rises with gun tragedies Republicans are headed for a disappointing end to their year in power Obama's HHS secretary could testify in Menendez trial MORE (D-Nev.) has struggled to find a replacement for Sen. Bob MenendezRobert (Bob) MenendezOvernight Health Care: House passes 20-week abortion ban | GOP gives ground over ObamaCare fix | Price exit sets off speculation over replacement You want to recall John McCain? Good luck, it will be impossible Poll: Most in NJ want Menendez to resign if found guilty MORE (D-N.J.), whose own seat is up in 2012.

Reid reportedly asked Sen. Charles SchumerCharles (Chuck) Ellis SchumerOvernight Health Care: Schumer calls for tying ObamaCare fix to children's health insurance | Puerto Rico's water woes worsen | Dems plead for nursing home residents' right to sue Crying on TV doesn't qualify Kimmel to set nation's gun agenda Trump knocks ‘fake’ news coverage of his trip to Puerto Rico MORE (D-N.Y.), who headed the committe in 2006 and 2008, to take the helm for a third time but Schumer declined. Reid also approached a number of other senators about the job, including Sens. Michael BennetMichael Farrand BennetAmeriCorps hurricane heroes deserve a reward — don’t tax it Joe Buck defends 'nonviolent protests' at NFL games Patriotism is no defense for Trump’s attacks on black athletes MORE (D-Colo.) and Mark WarnerMark Robert WarnerTrump: Why isn't Senate looking into 'Fake News Networks'? 5 takeaways from Senate Russian meddling presser Trump: 'America is truly a nation in mourning' MORE (D-Va.), but they too declined.

Murray just won her own difficult reelection bid.

Republicans are bullish on taking back the Senate majority in 2012 after capturing six seats this fall. High of the list of GOP targets in two years are Sens. Ben Nelson (D-Neb.), Claire McCaskillClaire Conner McCaskillKoch-backed group targets red-state Dems on tax reform Overnight Cybersecurity: Equifax security employee left after breach | Lawmakers float bill to reform warrantless surveillance | Intel leaders keeping collusion probe open Las Vegas highlights Islamist terrorism is not America's greatest domestic threat MORE (D-Mo.), Jim Webb (D-Va.) and Joe ManchinJoseph (Joe) ManchinOvernight Energy: EPA aims to work more closely with industry Overnight Finance: Lawmakers grill Equifax chief over hack | Wells Fargo CEO defends bank's progress | Trump jokes Puerto Rico threw budget 'out of whack' | Mortgage tax fight tests industry clout Lawmakers try again on miners’ pension bill MORE (D-W.Va.).

-- This post was updated at 12:31 p.m.