Mississippi state Sen. Chris McDaniel (R) is out with his first ad in his race against Sen. Thad CochranThad CochranOvernight Finance: GOP offers measure to repeal arbitration rule | Feds fine Exxon M for Russian sanctions violations | Senate panel sticks with 2017 funding levels for budget | Trump tax nominee advances | Trump unveils first reg agenda Senate committee ignores Trump, House budgets in favor of 2017 funding levels Overnight Finance: CBO finds 22M more uninsured under Senate health bill | GOP agrees ObamaCare taxes must go | Supreme Court to look at Dodd-Frank whistleblower protections | More tax reform hearings | Green light for partial travel ban | MORE (R-Miss.), a spot touting his conservative views that takes a subtle dig at Cochran.

"Mississippi is my home. I was born here. I love raising my family here. I'm Chris McDaniel, and I approve this message because our politicians in Washington have forgotten our conservative Mississippi values," he says before advocating for prayer in schools and the second amendment and knocking ObamaCare and "more wasteful spending."

"That's the type of constitutional conservatism we need in D.C.," he closes.

The primary hopeful's campaign called the buy "significant" and that the ad will run on broadcast and cable statewide. 

McDaniel is likely conservatives' best hope to knock off an incumbent GOP senator this election. While this is his first ad, his allies — including the Club for Growth and Senate Conservatives Fund — have been on the air backing his campaign and attacking Cochran for months.