Last month, Akin said that pregnancy rarely happens in cases of "legitimate rape" because women's bodies have a way of preventing conception.
Most recently, after their debate last week, Akin said incumbent Sen. Claire McCaskill (D) came out like a "wildcat" and characterized her behavior was more "ladylike" during her first Senate campaign in 2006.
Akin has apologized repeatedly for the first remark, while supporters and their funding made a quick retreat.
Still, in recent days, some Republicans have backed off their earlier criticism of Akin.
Akin has received support from DeMint's group, along with Sens. Lindsey Graham (R-S.C.) and Tom Coburn (R-Okla.) as the focus has shifted to winning back the majority in the Senate.
Sen. Roy Blunt, a fellow Missouri Republican, also weighed in on the Akin race Sunday.
Walking back his initial assertion that Akin should "step aside," Blunt said Missouri voters will overlook Akin's divisive comments and choose him for the sake of denying Sen. Harry Reid (D-Nev.) and the Democrats a majority in the next Congress.
"At the end of the day, that race does largely become a debate about the majority in the Senate," Blunt said on CNN's "State of the Union" program.
"He [Akin] is on a ticket, at a time, when people are looking at a Senate that's not doing its work, and the only way to change the Senate is to change the majority of the Senate.
"It becomes a party race," Blunt added.
Appearing beside Blunt, Maryland Gov. Martin O'Malley (D) had a decidedly different take. He said Akin "is going to lose because of [his] demonstrated anti-woman policy."
Last week, Republican National Committee Chairman Reince Priebus said Akin was "absolutely" a better option than McCaskill.
"That's a given, and as chairman of the party, I have an obligation to make sure we win as many seats in the Senate as possible."