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The ads both attack the Democratic candidates in each state — former U.S. Surgeon General Richard Carmona in Arizona and Rep. Joe DonnellyJoseph (Joe) Simon DonnellyMulvaney aims to cement CFPB legacy by ensuring successor's confirmation Election Countdown: Family separation policy may haunt GOP in November | Why Republican candidates are bracing for surprises | House Dems rake in record May haul | 'Dumpster fire' ad goes viral Actress Marcia Gay Harden urges Congress to boost Alzheimer's funding MORE in Indiana — for what they characterize as the candidates' comfort with raising taxes and support for President Obama's healthcare reform law.

But they also each assert that supporting the Democratic candidate would mean "a U.S. Senate controlled by liberals," as the ad running in Indiana states.

"Do you know that a vote for Carmona is a vote to put liberals in charge of the U.S. Senate?" the Arizona ad asks.

It's an interesting tactic, as the Senate currently has a Democratic majority. But it also might work in red-leaning states like Indiana and Arizona, where Mitt Romney has led Obama by double digits in a number of polls.

The Club for Growth boosted both Rep. Jeff FlakeJeffrey (Jeff) Lane FlakeTrump's move to halt family separations leaves questions unanswered Flake: Trump has 'unfortunately' redefined Republican Party Flake: Trump's attacks on Democrats 'bothersome,' unhelpful in immigration debate MORE (R-Ariz.) and Indiana State Treasurer Richard Mourdock (R) in their primaries with endorsements and funds, and both are running tight races against their Democratic challengers in states Republicans believe could help them regain a majority in the Senate.