And though she's clearly vulnerable going into 2014, she remains above water in both her approval and favorability, and defeats both announced challenger, Rep. Bill Cassidy (R), and another potential GOP contender, Chas Roemer.
Forty-eight percent of those polled see Landrieu favorably, while 42 percent have an unfavorable view of her. Her job approval rating is slightly closer, with only 44 percent approving of her job in the Senate, while 39 percent disapprove.
She leads Cassidy by five percentage points, with 46 percent support to his 41 percent support. Only 13 percent of voters remain undecided about that matchup, indicating the two will engage in a fierce fight over a small sliver of Louisiana votes.
Against Roemer, who is the son of former Gov. Buddy Roemer, Landrieu fares much better but still doesn't crack the 50 percent support that's considered comfortable for an incumbent heading into reelection. She takes 46 percent support to his 33 percent support, with 21 percent of respondents still unsure.
Republicans may be able to make some inroads against Landrieu's image if they do continue to hammer her on President Obama's healthcare law, however — 56 percent of those polled oppose it. An even larger majority, 60 percent, oppose gay marriage, which helps explain why Landrieu remains one of the last three Democratic Senators to decline to endorse the practice.
She has said that while she is not personally opposed to gay marriage, "my state has a very strong constitutional amendment against gay marriage and I think I have to honor that."
And Landrieu may face an anti-incumbent sentiment going into 2014, as 58
percent of those polled say Louisiana is going in the wrong direction.
But Landrieu may have an inroad against any Republican contender if she continues to hammer the Tea Party, as only a third of those polled agree with the Tea Party, while a third disagree and a third are unsure. That may be a tough case to make against Cassidy, however, who is considered one of the less conservative of the Republicans in the Louisiana delegation.
The poll was conducted among 541 likely voters from April 6-7 and has a margin of error of plus or minus 4.21 percentage points.