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The Tea Party-affiliated group is airing two weeks of radio ads attacking the senator in Atlanta, making him their fourth target, alongside Sens. Lindsey GrahamLindsey Olin GrahamGOP and Dems bitterly divided by immigration We are running out of time to protect Dreamers US trade deficit rises on record imports from China MORE (R-S.C.), Lamar AlexanderAndrew (Lamar) Lamar AlexanderOvernight Finance: Trump says shutdown 'could happen' | Ryan, conservatives inch closer to spending deal | Senate approves motion to go to tax conference | Ryan promises 'entitlement reform' in 2018 Senate approves motion to go to tax conference House conservatives, Ryan inch closer toward spending deal MORE (R-Tenn.) and Richard BurrRichard Mauze BurrSessions argued presidents can obstruct justice in Clinton impeachment trial Trump Jr. to meet with Senate panel amid Russia probe Trump’s Russian winter grows colder with Flynn plea deal MORE (R-N.C.). Like Burr, Isakson isn't up for reelection until 2016.

"Republicans in Congress can stop ObamaCare by refusing to fund it, but Sen. Johnny IsaksonJohn (Johnny) Hardy IsaksonSenate ethics panel wants details on sexual harassment allegations Senate leaders push tax debate into Friday Senate Ethics Committee opens 'preliminary inquiry' into Franken allegations MORE refuses to join the fight," the ad intones. "Johnny Isakson voted to give President Obama money to implement ObamaCare earlier this year, and he'll do it again if you don't make your voice heard."

The ad is part of a broader campaign to push Republicans to back Sen. Mike LeeMichael (Mike) Shumway LeeSupreme Court takes on same-sex wedding cake case House approves motion to go to tax conference — with drama Trump really will shrink government, starting with national monuments MORE's (R-Utah) campaign to use the impending debate over funding the government to try to force Democrats to defund ObamaCare. So far, 14 GOP senators have signed on, but a number of others have disagreed with the plan.