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The Tea Party-affiliated group is airing two weeks of radio ads attacking the senator in Atlanta, making him their fourth target, alongside Sens. Lindsey GrahamLindsey GrahamSpeaker Ryan faces crucial stretch March is the biggest month for GOP in a decade The Hill's 12:30 Report MORE (R-S.C.), Lamar AlexanderLamar AlexanderObamaCare quietly leaves mark on Medicare despite repeal push GOP governors confront Medicaid divide A guide to the committees: Senate MORE (R-Tenn.) and Richard BurrRichard BurrIntel Committee Dems huddle amid fight over Russia probe Heads of Intel panel diverge on Trump–Russia contacts Dems: GOP 'on notice' over Russia probes MORE (R-N.C.). Like Burr, Isakson isn't up for reelection until 2016.

"Republicans in Congress can stop ObamaCare by refusing to fund it, but Sen. Johnny IsaksonJohnny IsaksonA guide to the committees: Senate GOP rep on Trump: 'God has used imperfect people to do great things before' GOP senators unveil bill to give Congress control of consumer bureau budget MORE refuses to join the fight," the ad intones. "Johnny Isakson voted to give President Obama money to implement ObamaCare earlier this year, and he'll do it again if you don't make your voice heard."

The ad is part of a broader campaign to push Republicans to back Sen. Mike LeeMike LeeCruz, Lee, Paul demand 'full repeal' of ObamaCare Lessons from the godfather of regulatory budgeting Congress must reform civil asset forfeiture laws MORE's (R-Utah) campaign to use the impending debate over funding the government to try to force Democrats to defund ObamaCare. So far, 14 GOP senators have signed on, but a number of others have disagreed with the plan.