Recent polls show Patrick Murphy losing to Marco Rubio among Hispanics.
The ad uses an old clip of Toomey calling for an elimination of the corporate tax.
Democrat Deborah Ross leads GOP Sen. Richard Burr by 4 points in North Carolina.
The radio ad argues the incumbent Republican is important regardless of who wins the White House.
Money is being shifted to the North Carolina and Missouri Senate races.
Portman joked with Cincinnati Enquirer staffers beforehand that they should "make a big circle."
The labor union had previously backed Democrat Ted Strickland.
Republicans are attacking North Carolina's Deborah Ross over her work at the ACLU.
“He is asking us to let him get rich scamming America," Reid said.
Jason Kander is trailing Sen. Roy Blunt in polls.