Clinton said she can deal with "temper tantrums or their bullying," referring to Trump.
American Bridge runs through a litany of his controversial remarks on women in a new ad.
"I think that depends on Hillary Clinton," Katrina Pierson said.
Mattis was seen as a potential counter to Donald Trump.
"I’m not against anybody but I will be voting for Ted Cruz in the upcoming Republican primary."
"That doesn’t even count in a deck of cards," she said.
Trump has 41 percent support, with Cruz at 32 percent and Kasich at 21 percent.
Duckworth is trying to unseat GOP Sen. Mark Kirk, who is considered vulnerable this year.
She said John Boehner's remarks about Ted Cruz "were completely inappropriate."
Countering Trump, the Clinton campaign is offering a “woman card” for donations.