“I’m heartbroken and deeply saddened by the news," said Rep. Suzan Delbene.
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The move could hint at national ambitions.
A spokesman dismissed the idea that doctors returning from West Africa should be quarantined.
The two could face off in a 2016 presidential primary.
Mankiewicz, who also led George McGovern's presidential campaign, was 90.
Justin Sink 10/24/14 07:32 AM EDT
The president has championed a CDC "SWAT team" response.
"The war on terror is not over," the Kentucky Republican says.
The adviser posted the comment as a tweet, then deleted it and explained.
The New York City doctor had recently treated Ebola patients in West Africa.
He said electing Obama was a good start, but more can be done to combat discrimination.