Republicans launched a new television ad targeting Senate Majority Leader Harry ReidHarry ReidChris Murphy’s profile rises with gun tragedies Republicans are headed for a disappointing end to their year in power Obama's HHS secretary could testify in Menendez trial MORE (D-Nev.) as President Barack ObamaBarack Hussein ObamaAll five living former presidents to attend hurricane relief concert Overnight Health Care: Schumer calls for tying ObamaCare fix to children's health insurance | Puerto Rico's water woes worsen | Dems plead for nursing home residents' right to sue Interior moves to delay Obama’s methane leak rule MORE visited the state to help Reid campaign.

The Republican National Committee (RNC) released a new television ad on Friday that accuses the Senate Democratic leader and Obama of working to "tear down" the state's economy.

"As two of the most powerful politicians in Washington, this Democratic duo has schemed and forced their liberal agenda onto the people of Nevada, leading to 14 percent unemployment in the state, the highest in the nation," RNC Chairman Michael Steele said in a statement about the ad.

"Nevadans will surely have a lot of questions for a president and majority leader who have sold them out in favor of promoting their failed far-left tax-and-spend policies," Steele added. "Unfortunately, Harry Reid’s shameless devotion to President Obama’s job-killing agenda and his 30-year record of putting Washington first will do little to assuage their economic woes.”

Reid has been seen as vulnerable for much of the last year, in large part because of Nevada's high unemployment rate. The state also has seen the worst of the housing crisis.

Obama was in Las Vegas last night for a fundraiser for Reid, who's being targeted by Republicans in Washington for defeat in this fall's elections. Nevada Republicans settled on Sharron Angle as their choice to challenge Reid, who has a major campaign war chest.

The president hammered Angle during that appearance last night.

"I mean, look, Harry Reid’s opponent doesn’t just believe in these old, worn-out theories," he said. "On a lot of these issues, she favors an approach that's even more extreme than the Republicans we've got in Washington. That's saying something."

Obama also said voters in Nevada and other states face a choice between looking back to the GOP policies of the past or moving forward with Democratic policies, a theme the White House is expected to continue to weave into campaign appearances for the next several months.

"This is a choice between the policies that led us into the mess or the policies that are leading out of the mess," he said. "This is the choice between falling backward or moving forward. Now, I don't know about you, but Harry Reid wants to move forward." 

Angle's campaign released its own ad this morning, too, hitting Reid over the economy. The ad depicts workers who are assumed to be out of work, and showcases headlines about the dismal economic and employment numbers in the state.

"Help is on the way," the ad says, ending on a hopeful chord for Angle.

The RNC ad takes direct aim at Obama and Reid on the issue of the economy, where Nevadans have been especially hard-hit by the housing market's collapse. While Obama won Nevada's electoral votes in the 2008 presidential election, Republicans appear to think linking Reid to Obama will help them defeat the majority leader.

"Obama and Reid are a bust," the ad says.

It was not immediately clear how much the RNC had spent on the ad, or for how long or in what markets it would air.

View it below:

View Angle's ad here:

Updated 10:30 a.m.