Hoyer’s office announced that his chief of staff, Terry Lierman, will be leaving Capitol Hill at the end of the year, and will be replaced by the congressman’s current floor director, Alexis Covey-Brandt.

Lierman, who has served as Hoyer’s chief of staff since 2007, is leaving to start a venture capital company, according to a statement from Hoyer’s office.

His departure comes one month after Hoyer lost another top aide to the private sector, Deputy Chief of Staff Stacey Bernards.

Seeking to preempt suggestions that the departures are a signal about Hoyer’s future in Congress, Hoyer reminded reporters in his weekly briefing that he had recently filed to run for reelection in 2012.

Hoyer, 72, said that while he is sad that Terry is leaving, he is excited about Covey-Brandt’s promotion to chief of staff.

“Alexis brings great management skills, policy knowledge and political savvy to her new job,” Hoyer said in a news release. “I am fortunate to have her leading our efforts in the future.”

Lierman will continue to work for Hoyer by serving as treasurer for Hoyer's reelection campaign and chairman of Hoyer’s leadership PAC, AMERIPAC.