"Forget Democrats, for the good of the country, I think it's really important for the president to make the race he is running against the do-nothing Congress," she said on CNN's "State of the Union."
Pelosi said Democrats do not feel stung by the president setting his sights on Congress, given that the American people are just as frustrated with the legislative body.
"I have no problem with the president's statement," she said. "We want the president to run the race that's good for the country, and this do-nothing Congress must be defeated."
Pelosi also vowed, if re-elected, to remain in office at least through 2014. Speculation spiked that Pelosi might be eyeing an end to her career as a lawmaker, after her daughter said in an interview with a conservative site that she wanted to retire. Pelosi's office has called that claim "totally untrue."
"There's no greater honor for me than being the representative of San Francisco," Pelosi said.