By Alicia M. Cohn - 09/05/12 01:00 PM EDT
Penn's own speech on Tuesday evening, where he joked that the president's address had been mistakenly queued up on his teleprompter and zinged Clint Eastwood's "invisible Obama" routine, gave a taste of the type of irreverent event host he will be online.
A short clip of Penn's sit-down conversation with Biden hints at humor, as well, with the actor questioning Biden about his often-worn aviator sunglasses.
"I've been wearing these since I've been 17 years old," Biden says in the video. Both Biden and Penn then don aviators before fist-bumping for the camera.
Obama's campaign is heavily promoting neighborhood watch parties taking place on Thursday, the final night of the convention, sending out targeted emails announcing locations that also promise that the Penn-hosted “Live From Charlotte" livestream will be a must-see.
The interviews with Biden and Michelle Obama are set to stream before Obama speaks, starting at 8 p.m. EDT on Thursday. The "Live from Charlotte" special also features other "campaign officials and special guests," according to the Obama campaign.
Penn, best known for his roles in the comedic "Harold & Kumar" movie series as well a regular role on the Fox medical drama "House," was involved with Obama's 2008 campaign and worked at the White House as Obama’s associate director of public engagement for two stints in-between acting gigs. He is a national co-chairman for the 2012 campaign.