Biden was then asked if his plan was to use a rope-a-dope strategy of making himself look weak to make Ryan overconfident and slip up.
"You ever see me rope-a-dope?" Biden said.
Biden is set to square off against Ryan Thursday night in Danville, Ky., during the only vice presidential debate of this cycle.
Democrats are hoping for a strong debate performance by the vice president to turn the corner after a disappointing performance by President Obama against Mitt Romney during the first presidential debate a week earlier.
A day earlier Ryan also said he was excited about the debate.
"I'm not intimidated; I'm actually excited about it," Ryan said according to CNN.