It is the second year of the annual forum. In 2012, former CIA Director David Petraeus and actor Ben Affleck headlined the event.
According to organizers, the discussion will be focused around the topic, "How Can We Promote Freedom and Democracy Effectively?"
"We at Arizona State University are proud to have Vice President Biden and so many other distinguished leaders involved with the McCain Institute," said Arizona State University President Michael Crow in a statement. "Their participation in the Sedona Forum ensures a thought-provoking weekend."