Vice President Biden and Sen. Ted CruzRafael (Ted) Edward CruzOvernight Health Care: Trump eases rules on insurance outside ObamaCare | HHS office on religious rights gets 300 complaints in a month | GOP chair eyes opioid bill vote by Memorial Day HHS official put on leave amid probe into social media posts Trump, Pence to address CPAC this week MORE (R-Texas) are headlining events in South Carolina on Friday night as they consider bids for the White House in 2016.

Biden is delivering the keynote address at the South Carolina Democratic Party's 2013 Jefferson-Jackson Dinner at the Columbia Metropolitan Convention Center, according to the White House. Biden will also visit Rep. Jim Clyburn's (D-S.C.) fish fry at the Carolina Field House.

Just a few miles away, Cruz will deliver the keynote address at the South Carolina Republican Party's Silver Elephant Dinner. The dinner will honor former Sen. Jim DeMint (R-S.C.), a kingmaker in conservative politics who is now at the Heritage Foundation.

Both Biden and Cruz are mulling a run for president in 2016, and South Carolina is a key early primary state in the nominating process for both parties. Presidential hopefuls make visits to the state to gauge enthusiasm for their candidacies.

Biden has been asked a number of times whether he will run for president in 2016 and has always left the door open.

Cruz, a Tea Party favorite and rising star in the GOP, is considering a run for president as well, according to National Review.