The book, set to be published in the spring of 2014, will focus on Warren's "improbable rise from a working class family in Oklahoma to the United States Senate," the publisher told the Boston newspaper.
The book will also provide a “rousing call for protecting the middle class,” the publishing house said.
Although Henry Holt isn't revealing the advance Warren is receiving for writing the book, some of the total proceeds from sales will go to OneFund Boston, which seeks to aid victims of the Boston Marathon terror attack.
In March, Warren announced that she was working on a manuscript entitled Rigged. At the time the senator said the book would be an account of her time in Washington working to pass tougher regulations on Wall Street.
Warren is being represented by Robert Barnett, a prominent Washington lawyer who has been involved in a number of book projects by high profile current and former lawmakers. Barnett is also involved in a book project by Rep. Paul Ryan (R-Wis.).
Warren, who was a professor at Harvard law, before being tapped to work in the Obama administration, has written a number of books and scholarly articles before.