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McCain's tweet on Wednesday came after the White House announced that Donilon was stepping down from his post and that Rice would replace him.

Former foreign policy adviser Samantha PowerSamantha PowerUS to vote against UN resolution condemning Cuba embargo Former AG Lynch to meet with House, Senate Russia investigators The Memo: Tillerson flap puts spotlight on Trump's foreign policy moves MORE will replace Rice as ambassador to the United Nations.

Obama will make the announcement at 2:15 p.m.