The Chamber of Commerce on Sunday debuted a new national television ad featuring top Republicans stressing the need for comprehensive immigration reform, as the Senate prepares for its final week of votes on the landmark legislation.

The commercial features clips of top Republicans, including Sens. Marco RubioMarco RubioMexican politicians have a new piñata: Donald Trump Bush ethics lawyer: Congress must tell Trump not to fire Mueller The private alternative to the National Flood Insurance Program  MORE (R-Fla.), and Rand PaulRand PaulJudd Gregg: For Trump, reaching out would pay off This week: ObamaCare repeal vote looms over Senate Week ahead: Uncertainty surrounds ObamaCare repeal vote MORE (R-Ky.), and Rep. Paul RyanPaul RyanJudd Gregg: For Trump, reaching out would pay off Gingrich, small biz to launch major tax cut campaign GOP divided over care for transgender troops MORE (R-Wis.) discussing the ways in which the nation's immigration system is broken.

It will begin airing Monday as part of a seven-figure ad buy from the business lobby — the same day the Senate is scheduled to vote on a border security amendment expected to boost GOP support for the bill.

The so-called "border surge" amendment will nearly double the number of border patrol agents on the U.S.-Mexico border, as well as fund construction of 700 miles of fence.

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Rubio and Ryan have already announced support for the amendment and overall reform effort, although Paul told CNN on Sunday that he would vote against the bill.

In the clip, however, Paul is shown urging the country to "secure our borders, welcome our new neighbors and practice the values of freedom and family."

That sentiment is echoed by Rubio and Ryan in previous speeches highlighted in the ad.

"We all wish we didn't have this problem but leaving it the way it is, it's amnesty. We have to solve this problem," Rubio said.

The commercial will air on cable and radio stations, and a narrator makes the case that the immigration program reflects conservative values.

"Call Congress. End de facto amnesty. Create jobs and economic growth by supporting conservative immigration reforms," the narrator says.

The ad comes as the administration also is rallying support among business leaders, with President Obama meeting in the afternoon with nine executives at the White House to discuss the immigration bill.