House Speaker Nancy Pelosi (D-Calif.) said she was glad to see talks between U.S. and Iran over the Islamic state's nuclear program, but she questioned that the tone of Iranian President Mahmoud Ahmadinejad in a recent interview.

"Well, first I was chilled by his, sort of, smirk and laughter when he was talking about -- was asked about the processing of nuclear materials. That is no laughing matter," she said Monday on NBC's "Today" after seeing an interview with Ahmadinejad. "So I don't know what his point was there."

She added: "This does represent an opening in terms of him saying he'll try to find common ground."

Pelosi also said that the negotiations, which involve five other countries and were joined by the United States last weekend, were "very important."

"Remove all doubt or any excuse that he may have that there hasn't been some engagement, some communication," she said. "But it's not just the United States, mind you, it's many countries, leading countries, in the world coming together... and just saying, 'If you say you don't want a bomb, then here's a way to prove that.'"