Senate Majority Leader Harry ReidHarry ReidHopes rise for law to expand access to experimental drugs If Gorsuch pick leads to 'crisis,' Dems should look in mirror first Senate confirms Mulvaney to be Trump’s budget chief MORE (D-Nev.) on Monday moved to hold a vote this week on increasing the federal minimum wage.

Reid filed cloture on the motion to proceed to legislation from Sen. Tom HarkinTom HarkinGrassley challenger no stranger to defying odds Clinton ally stands between Sanders and chairmanship dream Do candidates care about our health or just how much it costs? MORE (D-Iowa) that would increase the minimum wage from $7.25 to $10.10 per hour.

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The vote will be a major test of unity for Senate Democrats, who have made the wage hike central to their populist agenda for the midterm elections. 

Some vulnerable Democrats up for reelection have expressed concern about the wage increase, citing a Congressional Budget Office report that Harkin’s bill would harm job growth. Some of them have come out in support of a smaller increase to $9 an hour, proposed by Sen. Susan CollinsSusan CollinsGOP senator won't vote to defund Planned Parenthood GOP senator grilled over DeVos vote during town hall GOP senator: Flynn should testify on Russia MORE (R-Maine).

If Democrats were to stick together on the wage vote, they would need at least five Republicans to vote with them to advance the measure. 

But Republicans are unified against it, which has put pressure on Democrats to minimize defections in their 55-member caucus.

Sen. Mark PryorMark PryorCotton pitches anti-Democrat message to SC delegation Ex-Sen. Kay Hagan joins lobby firm Top Democrats are no advocates for DC statehood MORE (D-Ark.) has said he’ll vote against the increase to $10.10 per hour, but other vulnerable Democrats up for reelection have signaled they would support it.

Most Democrats are insisting on the $10.10 wage level because they say it would lift all full-time workers out of poverty.