Prior to the vote on passage, which is set for after 4 p.m., the upper chamber will engage in five-hours of debate and votes on three amendments that pertain to the legislation. 

The most controversial amendment of the three is sponsored by Sen. Tom CoburnThomas (Tom) Allen CoburnPaul Ryan should realize that federal earmarks are the currency of cronyism Republicans in Congress shouldn't try to bring back earmarks Republicans should know reviving earmarks is a political nightmare MORE (R-Okla.) and in effect would prohibit the federal government from using funds raised through patent fees for unrelated purposes.

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 The House already rejected similar language contained in that amendment, and earlier in the day Sen. Patrick LeahyPatrick Joseph LeahyGrassley, Dems step up battle over judicial nominees Popular bill to fight drug prices left out of budget deal Judiciary Dems want public hearings with Kushner, Trump Jr. MORE (D-Vt.), who is the floor manager for the patent bill, said its additon would likely “kill” patent reform efforts.

The other two amendments offered by Sens. Jeff SessionsJefferson (Jeff) Beauregard SessionsUnder pressure, Trump shifts blame for Russia intrusion Overnight Tech: Judge blocks AT&T request for DOJ communications | Facebook VP apologizes for tweets about Mueller probe | Tech wants Treasury to fight EU tax proposal Overnight Regulation: Trump to take steps to ban bump stocks | Trump eases rules on insurance sold outside of ObamaCare | FCC to officially rescind net neutrality Thursday | Obama EPA chief: Reg rollback won't stand MORE (R-Ala.) and Maria CantwellMaria Elaine CantwellDemocrats request info on 'repeated environmental concerns' at Ohio pipeline Booker to stop accepting donations from corporate PACs Gillibrand vows to refuse donations from corporate PACs MORE (D-Wash.), pertain to patent term extensions and a transitional program for covered business method patents, respectively.

Before adjourning the Senate at about 8 p.m. Reid also outlined the schedule for the rest of the week saying the Senate would move to a procedural vote on a joint resolution of disapproval of the president’s exercise of authority to increase the debt limit. That vote will occur after President Obama delivers his "jobs" speech to a joint session of Congress on Thursday night.

Reid said if that resolution is taken up he might hold the Senate open “for a long time” on Friday to "dispose" of it.

The Senate is set to return at 9:30 a.m. on Thursday.