"We ought not to be mitigating the sequester's effect on just one segment when children, the sick, our military and many other groups who will be impacted by this irresponsible policy will be left unhealed," Hoyer said.

Pelosi made similar comments during debate and in a tweet after the vote. "Airports shouldn't be subjected to politics, neither should our seniors or children," she tweeted.

During the debate, she agreed that the FAA shouldn't be politicized and added, "neither should the education of our children, the nutrition for our seniors — 4 million Meals on Wheels — tens of thousands of children thrown off Head Start, our defense."

Nonetheless, Pelosi voted for the bill and Hoyer did not. She was one of 159 Democrats who supported the bill, including House Democratic Caucus Chairman Xavier BecerraXavier BecerraColorado joins states adopting stricter vehicle emissions standard Overnight Energy: New controversies cap rough week for Pruitt | Trump 'not happy about certain things' with Pruitt | EPA backtracks on suspending pesticide rule EPA backpedals on suspending pesticide rule following lawsuit MORE (Calif.).

During the debate, Pelosi was not specific about whether she would vote for the bill and blamed Republicans for forcing the issue. She said the lack of a House-Senate conference on the budget is why the sequester is still in place, implying that a budget deal would help get around the sequester.

"We are here because of the refusal of the Republicans to come to the table for a conference," she said.

Among the 28 Democrats who joined Hoyer in opposing the bill were Rep. John Dingell (Mich.), the longest-serving House member, House Judiciary Committee ranking member John Conyers (Mich.), Congressional Black Caucus Chairwoman Marcia FudgeMarcia Louise FudgeDeVos grilled on civil rights for students Farm bill abandons endangered wildlife House rejects effort to condemn lawmaker for demanding 'Dreamer' arrests MORE (Ohio), and Budget Committee ranking member Chris Van Hollen (Md.).

House GOP leaders were unified in support for the FAA bill, and 12 Republicans voted against it.