Sen. Ted CruzRafael (Ted) Edward CruzSenate Dems hold floor talk-a-thon against latest ObamaCare repeal bill Overnight Finance: CBO to release limited analysis of ObamaCare repeal bill | DOJ investigates Equifax stock sales | House weighs tougher rules for banks dealing with North Korea GOP state lawmakers meet to plan possible constitutional convention MORE (R-Texas) said Monday that Secretary of State John KerryJohn Forbes KerryBringing the American election experience to Democratic Republic of the Congo Some Dems sizzle, others see their stock fall on road to 2020 The Hill's 12:30 Report MORE should resign for allegedly saying that Israel risked becoming "an apartheid state" if it didn't agree to a peace deal.

“Secretary Kerry has proven himself unsuitable for the position he holds,” Cruz said on the Senate floor. “John Kerry should offer President Obama his resignation.”

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On Sunday, The Daily Beast reported that Kerry likened the Jewish state to South Africa's racist apartheid regime during a talk with a group of influential world leaders behind closed doors on Friday.

“There is no place for this word in the context of the state of Israel … because America will be with Israel regardless of the status of the diplomatic process,” Cruz said of Kerry's use of "apartheid." 

Kerry has been trying to broker a peace deal between Israel and the Palestinians but has suffered major setbacks this month with the Palestinian Authority forming a unity government with Hamas, which Israel considers a terrorist organization. That led Israel to suspend talks with the Palestinians.

Earlier Monday, House Majority Leader Eric Cantor (R-Va.) demanded Kerry apologize but didn't go as far as Cruz in calling for his resignation.