Sen. Ted CruzRafael (Ted) Edward CruzDebbie Wasserman Schultz marks 10 years as breast cancer survivor Foreign agent registration is no magical shield against Russian propaganda Let Trump be Trump and he'll sail through 2020 MORE (R-Texas) said Monday that Secretary of State John KerryJohn Forbes KerryLobbying world Kerry: Trump not pursuing 'smart' or 'clever' plan on North Korea Tillerson will not send high-ranking delegation to India with Ivanka Trump: report MORE should resign for allegedly saying that Israel risked becoming "an apartheid state" if it didn't agree to a peace deal.

“Secretary Kerry has proven himself unsuitable for the position he holds,” Cruz said on the Senate floor. “John Kerry should offer President Obama his resignation.”

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On Sunday, The Daily Beast reported that Kerry likened the Jewish state to South Africa's racist apartheid regime during a talk with a group of influential world leaders behind closed doors on Friday.

“There is no place for this word in the context of the state of Israel … because America will be with Israel regardless of the status of the diplomatic process,” Cruz said of Kerry's use of "apartheid." 

Kerry has been trying to broker a peace deal between Israel and the Palestinians but has suffered major setbacks this month with the Palestinian Authority forming a unity government with Hamas, which Israel considers a terrorist organization. That led Israel to suspend talks with the Palestinians.

Earlier Monday, House Majority Leader Eric Cantor (R-Va.) demanded Kerry apologize but didn't go as far as Cruz in calling for his resignation.