Sen. Ted CruzRafael (Ted) Edward CruzOvernight Health Care: Trump eases rules on insurance outside ObamaCare | HHS office on religious rights gets 300 complaints in a month | GOP chair eyes opioid bill vote by Memorial Day HHS official put on leave amid probe into social media posts Trump, Pence to address CPAC this week MORE (R-Texas) said Monday that Secretary of State John KerryJohn Forbes Kerry2020 Dem contenders travel to key primary states When it comes to Colombia, America is in a tough spot 36 people who could challenge Trump in 2020 MORE should resign for allegedly saying that Israel risked becoming "an apartheid state" if it didn't agree to a peace deal.

“Secretary Kerry has proven himself unsuitable for the position he holds,” Cruz said on the Senate floor. “John Kerry should offer President Obama his resignation.”

On Sunday, The Daily Beast reported that Kerry likened the Jewish state to South Africa's racist apartheid regime during a talk with a group of influential world leaders behind closed doors on Friday.

“There is no place for this word in the context of the state of Israel … because America will be with Israel regardless of the status of the diplomatic process,” Cruz said of Kerry's use of "apartheid." 

Kerry has been trying to broker a peace deal between Israel and the Palestinians but has suffered major setbacks this month with the Palestinian Authority forming a unity government with Hamas, which Israel considers a terrorist organization. That led Israel to suspend talks with the Palestinians.

Earlier Monday, House Majority Leader Eric Cantor (R-Va.) demanded Kerry apologize but didn't go as far as Cruz in calling for his resignation.