Ahead of the vote, Sen. Bob Corker (R-Tenn.), alongside Sens. Lamar Alexander (R-Tenn.) and Patrick Leahy (D-Vt.), the chairman of the Senate Judiciary Committee, urged the Senate to cleanly confirm Fowlkes.
"I'm glad to join with Sen. Alexander, with Sen. Leahy and others," Corker said. "I hope we have an overwhelming vote today with this gentleman who I believe is going to be an outstanding federal judge and I want to ask all of my colleagues to join us in supporting this person who, again, I think will be exemplary on the bench as he has been throughout his entire life."
President Obama nominated Fowlkes, formerly a state judge in Tennessee, in December 2011.