Senators voted Wednesday to head to a conference committee with the House on the budget. 

Lawmakers voted 54-43 on a motion to go to a conference committee, which will reconcile GOP budgets approved by both the House and the Senate. 

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Sen. Rand PaulRand PaulSanders, Dems defend ObamaCare at Michigan rally Paul: Medicaid expansion 'the big question' Rand Paul: ObamaCare replacement goal is to insure most people at lowest cost MORE (R-Ky.), who is running for president in 2016, was the only Republican to vote against going to conference. Sen. Marco RubioMarco RubioRubio wades into Trump-Lewis feud 19 companies that Trump has tweeted about Ex-Dem gov: I would have picked Giuliani over Tillerson MORE (R-Fla.), who is also running for president, voted in favor of going to conference.

Democratic Sens. Chris CoonsChris CoonsWHIP LIST: How many Dems will back Sessions? Sessions defends his record on race Overnight Tech: Tech listens for clues at Sessions hearing | EU weighs expanding privacy rule | Senators blast Backpage execs MORE (Del.), Tim KaineTim KaineLaura Ingraham mulling Senate run: report Schumer puts GOP on notice over ObamaCare repeal The Hill's 12:30 Report MORE (Va.) and Mark WarnerMark WarnerSenate Intel panel to probe Trump team's ties to Russia The Hill's 12:30 Report Blackout forces brief delay in Pompeo confirmation hearing MORE (Va.) and Independent Sen. Angus KingAngus KingWasserman Schultz confronted Comey about Russian hacking Maine senator: ‘I haven’t made my final decision’ on Pompeo Lawmakers press Comey on rumors of FBI probe into Trump camp MORE (Maine), who caucuses with Democrats, voted with Republicans. 

Sen. Bernie SandersBernie SandersThe Obama presidency that never was Trump education pick to face Warren, Sanders Sanders, Dems defend ObamaCare at Michigan rally MORE (I-Vt.), ranking member of the Senate budget committee, slammed the Republican budget ahead of the vote, saying that it would make cuts to health, education and nutrition programs.  

“This is reality,” he said. “This is the Republican budget.”

Sen. Mike EnziMike EnziSchumer puts GOP on notice over ObamaCare repeal Live coverage: The Senate's 'vote-a-rama' Senate heading toward late-night marathon session MORE (R-Wyo.), however, said moving forward with the budget was another step “in helping to change the way we do business here in Washington.”

Senators passed the Republican budget last month, and House lawmakers appointed their budget conferees on Tuesday.  Senators are expected to take additional votes on the conference committee later Wednesday. 

Members of Congress will use the conference committee to try to reconcile their separate budgets.