Senate Democrats on Wednesday blocked legislation from the House that would crack down on the resettlement of Syrian and Iraqi refugees in the United States.

The 55-43 vote came after Senate Minority Leader Harry ReidHarry ReidConservative Senate candidate calls on GOP to end filibuster Ex-Reid aide: McConnell's 'original sin' was casting ObamaCare as 'partisan, socialist takeover' GOP faces growing demographic nightmare in West MORE (D-Nev.) sought approval of a handful of amendments, including one on Donald TrumpDonald TrumpScaramucci says he will contact FBI, Justice Dept. over leaked financial disclosure Dem rep to introduce measure requiring White House to disclose pardons Lawmakers push to toughen foreign lobbying rules MORE's push to temporarily ban Muslims from entering the country.

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Republicans ripped the attempt to link the bill to the GOP presidential candidate. Senate Majority Whip John CornynJohn CornynGOP senator warns Trump: Panel won't take up attorney general nominee this year Bare bones repeal plan gains steam in Senate Overnight Healthcare: Senate rejects repeal-only ObamaCare plan | Ads target Heller, Capito over vote | Dem says ObamaCare repeal effort moving US 'toward single-payer' MORE (R-Texas) called the effort “ridiculous” and said Democrats were trivializing the refugee issue “by bringing the circus to town on the floor of the Senate.”

"I hate to see the Democratic leader try to trivialize this very important national security debate and discussion by injecting presidential election politics right in the middle of this," Cornyn said.

Democrats fired back, suggesting GOP leaders rejected Reid's deal because they were afraid of taking on their party’s presidential front-runner.

"When we offer them a chance to vote on another statement by Republican presidential nominee Mr. Trump ... they run like scalded cats," Sen. Dick DurbinDick DurbinDems don’t want to help GOP improve repeal bill Mnuchin: Trump administration examining online sales tax issue Senate Dem: We’re trying to block a recess appointment to replace Sessions MORE (D-Ill.) said. 

Sen. Bernie SandersBernie SandersSanders: Dems won't vote on 'sham' single payer amendment GOP Senator forces Dems to vote on single payer Kerry on Trump’s military transgender ban: ‘We’re better than this’ MORE (I-Vt.), who is running for the Democratic presidential nomination, missed the vote, as did Sen. Lindsey GrahamLindsey GrahamBare bones repeal plan gains steam in Senate Live coverage: Senate debates repealing ObamaCare Graham: Trump 'absolutely' showing weakness on Sessions MORE (R-S.C.).

The refugee legislation, which passed the House late last year, would "pause" the resettlement of Syrian and Iraqi refugees in the U.S. until the Obama administration certifies that they aren't a national security threat. Sixty votes were needed to move forward.

President Obama has threatened to veto the bill if it reaches his desk.

Speaker Paul RyanPaul RyanOvernight Tech: Trump touts new Wisconsin electronics plant | Lawmakers to unveil email privacy bill | Facebook funds group fighting election hacks Overnight Finance: Fed holds rates steady | Treasury chief looking at online sales taxes | White House, GOP close to releasing tax-reform principles Wisconsin Democrat refuses to be ‘backdrop’ in Trump’s jobs announcement MORE (R-Wis.) slammed Senate Democrats, calling their decision to block the legislation "irresponsible."

"Our approach balances security and compassion, and it was backed by a veto-proof majority in the House," he said.

Fighting over refugee resettlement has intensified amid rising fears about the Islamic State in Iraq and Syria (ISIS). Some worry the terrorist group could use the program to slip fighters into the U.S. and carry out attacks on American soil like the carnage the group unleashed in Paris last year. 

Senate Majority Leader Mitch McConnellMitch McConnellDems don’t want to help GOP improve repeal bill Bipartisan group of governors call on GOP to reject skinny repeal Dems get CBO scores on what they think skinny bill will look like MORE (R-Ky.) had suggested that senators shouldn't put a limit on amendments to the refugee legislation and that the onus was on Democrats to allow the votes.

"A better way to go forward would be to go to the bill, have an open amendment process, alternate from side to side. Senators should vote to go to the legislation," McConnell told reporters. 

But Durbin said McConnell's counteroffer wouldn’t guarantee the amendment votes Democrats were seeking.

"Sen. McConnell is a pro and is experienced, and he knows that any single senator could object to going to a roll call vote on any amendment," Durbin said.

Reid called the bill "just another step in the absolute wrong direction, the direction of Donald Trump." 

Republican senators had planned to offer amendments to the bill that would give governors the ability to reject refugees and require the Obama administration to include social media in refugee background checks.

GOP senators were also planning to try to make Democrats take politically sensitive votes.

Sen. Ted CruzTed CruzBare bones repeal plan gains steam in Senate Dem lawmaker: Trump should fire Sessions GOP Senate candidate: concerns about Trump are 'coming to fruition' MORE (R-Texas), who is running for president, said that he was planning to offer an amendment that would increase jail time for undocumented immigrants who reenter the country illegally. 

Known as "Kate's Law," the legislation is named after Kathryn Steinle, who was shot and killed in San Francisco. The suspect in her slaying is an illegal immigrant who had been deported five times. 

Even if Democrats had allowed Republicans to add the provisions, they could have blocked McConnell from ending debate on the bill.

The House legislation has underscored divisions among Senate Republicans over how to make the refugee resettlement process more secure.  

Sen. Jeff FlakeJeff FlakeOPINION | Healthcare vote a political death wish for GOP in 2018 Flake secretly wrote book on conservative politics: report Dem campaign arm slams Heller, Flake on healthcare votes MORE (R-Ariz.) said that while he doesn't support a "pause" of refugee acceptance, he backs moving forward with the legislation so that he could try to amend it.  

"I'm not a fan of this approach," Flake told reporters, adding that he planned to offer amendments to loosen new visa restrictions for dual nationals that were included in last months' government spending bill. 

Some conservative Republicans, on the other hand, argue the refugee bill doesn’t go far enough. 

Sen. Jeff SessionsJeff SessionsGOP senator warns Trump: Panel won't take up attorney general nominee this year Trump discussing attorney general recess appointment with advisers: report Scaramucci promises more 'dramatic steps' on ousting White House leakers MORE (R-Ala.) suggested late last year that the House bill would allow Obama to bring in as many refugees as he wants, adding that it "fails to defend" American interests. 

Updated at 5:31 p.m.