“We have not had a confirmed administrator since 2006,” Sen. Tim KaineTimothy (Tim) Michael KaineKaine demands answers on Pentagon missions in Africa Lawmakers push for House floor debate on war authorization Defense bill moves forward with lawmakers thinking about McCain MORE (D-Va.) said ahead of the vote. “It will be a good thing for the mission and the country to confirm an administrator.”

Republican Sens. Ted CruzRafael (Ted) Edward CruzPro-Trump super PAC raises .5 million in 6 weeks Trump has exposed Democratic hypocrisy on prison reform Tapper lists 'conspiracy theories' Trump has shared MORE (Texas), Ron JohnsonRonald (Ron) Harold JohnsonHouse GOP sets three FBI interviews in Clinton probe Overnight Health Care — Sponsored by PCMA — House passes 'right to try' drug bill | Trump moves to restrict abortion referrals House approves 'right to try,' sends bill to Trump's desk MORE (Wis.), Mike LeeMichael (Mike) Shumway LeeTrump has exposed Democratic hypocrisy on prison reform Denial of services to same-sex couples can harm their health GOP Senate primary heats up in Montana MORE (Utah), Mike CrapoMichael (Mike) Dean CrapoOvernight Finance: Trump signs Dodd-Frank rollback | Snubs key Dems at ceremony | Senate confirms banking regulator | Lawmakers lash out on Trump auto tariffs Trump signs Dodd-Frank rollback Overnight Finance: House sends Dodd-Frank rollbacks to Trump | What's in the bill | Trump says there is 'no deal' to help ZTE | Panel approves bill to toughen foreign investment reviews MORE (Idaho), James Risch (Idaho), Mitch McConnellAddison (Mitch) Mitchell McConnellMcConnell says he backs Mueller probe after classified briefing Overnight Finance: Trump signs Dodd-Frank rollback | Snubs key Dems at ceremony | Senate confirms banking regulator | Lawmakers lash out on Trump auto tariffs Senate Dems’ campaign chief ‘welcomes’ midterm support from Clintons MORE and Rand PaulRandal (Rand) Howard PaulPro-Trump super PAC raises .5 million in 6 weeks Trump has exposed Democratic hypocrisy on prison reform Overnight Energy: Reporters barred from Day 2 of EPA summit | Dems blame Trump for gas price increases | Massachusetts to get new offshore wind farm MORE (Ky.) voted against Tavenner's nominations.

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Sen. Tom HarkinThomas (Tom) Richard HarkinDem Senator open to bid from the left in 2020 Senate GOP rejects Trump’s call to go big on gun legislation Trump should require federal contractors to follow the law MORE (D-Iowa) had placed a hold on her nomination out of frustration with the administration’s plan to spend prevention funds on promotions for the Affordable Care Act. He lifted the hold earlier this month after he said enough light had been shined on the issue.

CMS administers the Medicare and Medicaid programs and is also charged with implementing most of Obama's healthcare law. Tavenner has been leading CMS on an acting basis.

Kaine said Tavenner, who is from Virginia, was the right pick because she would bring a patient-focused “nurse’s attitude” to CMS and she is an “expert” on finding healthcare cost savings.

Before the vote on Tavenner, the Senate also voted to approve the nomination of William Orrick to be U.S. District Judge for the Northern District of California. He was confirmed on a 56-41 vote.

Sen. Barbara BoxerBarbara Levy BoxerThe ‘bang for the buck’ theory fueling Trump’s infrastructure plan Kamala Harris endorses Gavin Newsom for California governor Dems face hard choice for State of the Union response MORE (D-Calif.) said she was glad Orrick got a vote because the Northern District of California has a judicial emergency with a caseload 24 percent higher than the national average.

“We all know justice delayed is justice denied,” Boxer said. “That’s why I’m excited we’re finally getting a vote on this nominee.”

Sen. Chuck GrassleyCharles (Chuck) Ernest GrassleyFormer US attorneys urge support for Trump nominee Dem leaders request bipartisan meeting on Russia probe Overnight Health Care — Sponsored by PCMA — House passes 'right to try' drug bill | Trump moves to restrict abortion referrals MORE (R-Iowa) said he opposed Orrick's nomination because he  didn't like a judicial decision he made that maintained the “weak status quo” of immigration and border enforcement. He added that Orrick didn't answer all of his questions during his confirmation hearing with the Judiciary Committee, where Grassley serves as the ranking member.