Most Republican senators voted against Dorsey's confirmation — Sen. Susan CollinsSusan Margaret CollinsOvernight Tech: Judge blocks AT&T request for DOJ communications | Facebook VP apologizes for tweets about Mueller probe | Tech wants Treasury to fight EU tax proposal Overnight Regulation: Trump to take steps to ban bump stocks | Trump eases rules on insurance sold outside of ObamaCare | FCC to officially rescind net neutrality Thursday | Obama EPA chief: Reg rollback won't stand FCC to officially rescind net neutrality rules on Thursday MORE (Maine) voted for her.

Senate Judiciary Committee ranking member Chuck GrassleyCharles (Chuck) Ernest GrassleyPavlich: The claim Trump let the mentally ill get guns is a lie Congress fails miserably: For Asian-Americans, immigration proposals are personal attacks Grassley, Dems step up battle over judicial nominees MORE (R-Iowa) said he opposed Dorsey’s nomination because she has no criminal law experience and there are unanswered questions about campaign donations she has made.

“We want judges who will be restrained by precedent and laws Congress passes,” Grassley said. “I’m unconvinced she’ll be able to lay her policy preferences aside.”

The Senate is expected to consider several more of the president’s nominees before leaving for the August recess. But if Republicans continue to block Obama's cabinet nominees, some Democrats have pushed for the "nuclear option" — changing the rules on a simple-majority vote. It is unclear if it will come to that.

Earlier Tuesday, Senate Minority Leader Mitch McConnellAddison (Mitch) Mitchell McConnellLawmakers feel pressure on guns Bipartisan group of House lawmakers urge action on Export-Import Bank nominees Curbelo Dem rival lashes out over immigration failure MORE (R-Ky.) accused Democrats of “cooking up phony nomination fights.”

“Already in this Congress, the Senate has approved 27 of President Obama’s lifetime appointments. That compares to just 10 at a comparable point in President Bush’s second term,” McConnell said. “In other words, President Obama has just settled back into office, and already he’s secured nearly three-times more comparable judicial confirmations.”