The Senate is expected to vote on final confirmation of Tom Perez to be the secretary of Labor Thursday afternoon and whether to end debate on Gina McCarthyGina McCarthyBusiness leaders must stand up and 'March for Science' on Saturday Trump isn't saving the coal industry. He's letting it compete. EPA chief: ‘Help is on the way’ for farmers MORE’s nomination to lead the EPA shortly after that.

McConnell accused Perez of making “misleading” statements to Congress and an inspector general while running the Civil Rights Division of the Department of Justice.

“This is reflective of not some passionate left-winger … but a crusading ideologue who believes the law simply doesn’t apply to him,” McConnell said. “His ideological passion is what’s so troubling to me about Mr. Perez.”

Senate Majority Leader Harry ReidHarry ReidDraft House bill ignites new Yucca Mountain fight Week ahead: House to revive Yucca Mountain fight Warren builds her brand with 2020 down the road MORE (D-Nev.) defended Perez saying he has a “proven track record of public service.”

Republicans have objected to McCarthy not because she isn’t qualified, but because she would implement President Obama’s new regulation of carbon emissions from power plants. McCarthy currently serves as the EPA’s top air quality regulator.

“She’s overseen the implementation of numerous job-killing regulations,” McConnell said. “They’ve helped bring upon a depression.”

Reid argued she is a bipartisan choice because she formerly worked for then-Gov. Mitt Romney (R-Mass.).

Republicans agreed to hold an up-or-down vote on the nominees as part of a deal to avoid Senate rule changes limiting the minority's right to filibuster executive branch nominees.

Reid said he hoped the Senate would complete business on both nominations by the end of Thursday.