Sen. John Kerry (D-Mass.) is known for being one of the more athletic members of Congress and this summer he's hitting the road on two wheels. Again.

Kerry will ride his bike 110 miles in the 2010 PanMass Challenge, an annual bicycle race that raises money for cancer research.

And while the ride will mark Kerry's seventh time racing in the event, this year the cause is even more personal.

As he reminded supporters in an email on Wednesday, Kerry's wife, Teresa Heinz Kerry, is battling breast cancer. She was diagnosed last winter.

The senator also lost his dear friend, the late Sen. Edward Kennedy (D-Mass.), to brain cancer last summer. 

In a first for the PanMass Challenge, this year the state's other senator, and Kennedy's replacement, Sen. Scott Brown (R) will pedal the 110 mile course.

Since joining the Senate in January, Brown has participated in basketball games, softball tournaments, and charity running races, so he's likely to be in good shape for the bike challenge.

As for Kerry, he promises, "I'll give every ounce of energy I have on that 110-mile ride."

The race takes place Aug. 1-2, and donations will benefit the Jimmy Fund.