There was speculation in December of last year that Affleck would run for Senate in Massachusetts, to replace Secretary of State John KerryJohn KerryFormer Obama officials say Netanyahu turned down secret peace deal: AP How dealmaker Trump can resolve the Israeli-Palestinian conflict John Kerry to teach at Yale on global issues MORE. Affleck, a Boston native, and Kerry are close. The actor campaigned for Kerry's presidential campaign in 2004.

ADVERTISEMENT
But Affleck opted not to run and has seen his Hollywood career flourish: His film "Argo" won the Academy Award for Best Picture earlier this year.

Affleck has remained politically active through his Eastern Congo Initiative and he's testified on Capitol Hill about ending the war in the Congo. He also held a fundraiser for Massachusetts Democrat Elizabeth WarrenElizabeth WarrenDeVos should ‘persist’ despite liberal opposition AT&T, Time Warner defend deal Scott Brown being considered for ambassador to New Zealand: report MORE's 2012 Senate campaign.

Garner said she would support her husband if he makes the political leap.

"I'm along for the ride," she told the magazine.