There was speculation in December of last year that Affleck would run for Senate in Massachusetts, to replace Secretary of State John KerryJohn Forbes KerryJohn Kerry to NYU Abu Dhabi: We can't address world problems by 'going it alone' Juan Williams: Trump's dangerous lies on Iran Pompeo: US tried, failed to achieve side deal with European allies MORE. Affleck, a Boston native, and Kerry are close. The actor campaigned for Kerry's presidential campaign in 2004.

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But Affleck opted not to run and has seen his Hollywood career flourish: His film "Argo" won the Academy Award for Best Picture earlier this year.

Affleck has remained politically active through his Eastern Congo Initiative and he's testified on Capitol Hill about ending the war in the Congo. He also held a fundraiser for Massachusetts Democrat Elizabeth WarrenElizabeth Ann WarrenRising star Abrams advances in Georgia governor race Progressive rise is good news for Sanders, Warren Juan Williams: Trump gives life to the left MORE's 2012 Senate campaign.

Garner said she would support her husband if he makes the political leap.

"I'm along for the ride," she told the magazine.