There was speculation in December of last year that Affleck would run for Senate in Massachusetts, to replace Secretary of State John KerryJohn Forbes KerryBringing the American election experience to Democratic Republic of the Congo Some Dems sizzle, others see their stock fall on road to 2020 The Hill's 12:30 Report MORE. Affleck, a Boston native, and Kerry are close. The actor campaigned for Kerry's presidential campaign in 2004.

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But Affleck opted not to run and has seen his Hollywood career flourish: His film "Argo" won the Academy Award for Best Picture earlier this year.

Affleck has remained politically active through his Eastern Congo Initiative and he's testified on Capitol Hill about ending the war in the Congo. He also held a fundraiser for Massachusetts Democrat Elizabeth WarrenElizabeth Ann WarrenSenate Dems hold floor talk-a-thon against latest ObamaCare repeal bill Trump bets base will stick with him on immigration Dems call for action against Cassidy-Graham ObamaCare repeal MORE's 2012 Senate campaign.

Garner said she would support her husband if he makes the political leap.

"I'm along for the ride," she told the magazine.