Democratic National Committee Chairwoman Debbie Wasserman Schultz (D-Fla.) called it "a proud moment." Rep. Jared Polis (D-Colo.), the first openly homosexual member of Congress who is also a parent, thanked Obama in a tweet.

Sen. Jeff MerkleyJeffrey (Jeff) Alan MerkleyEarly tax bill reality very different than Democratic rhetoric Senate GOP seeks to change rules for Trump picks Dem senators tear into Trump: Tax bill 'a very big Christmas gift from Trump to himself' MORE (D-Ore.) called the announcement “HUGE” in a tweet. Sen. Chris CoonsChristopher (Chris) Andrew CoonsA Department of Energy foundation: An idea whose time has come We must reconcile privacy and safety in the digital era Protecting intellectual property in America is harder than ever MORE (D-Del.) called it “a historic step.”

Sen. Kirsten GillibrandKirsten Elizabeth GillibrandTrump thinks he could easily beat Sanders in 2020 match-up: report Listen: EMILY’s List upbeat about Dem House in '19 Desperate Democrats shouldn't settle for Oprah MORE ‏ (D-N.Y.) thanked the president for his leadership on LGBT equality and later went on to ask her followers to join her in expressing their public support for the president. And Rep. Nita Lowey (D-N.Y.) said all Americans deserve to have a long and happy marriage like her own.

Democrats including Sens. Mark UdallMark Emery UdallDemocratic primary could upend bid for Colorado seat Picking 2018 candidates pits McConnell vs. GOP groups Gorsuch's critics, running out of arguments, falsely scream 'sexist' MORE (Colo.) and Charles SchumerCharles (Chuck) Ellis SchumerDemocrats will need to explain if they shut government down over illegal immigration White House: Trump remarks didn't derail shutdown talks Schumer defends Durbin after GOP senator questions account of Trump meeting MORE (N.Y.), Reps. Jim Himes (Conn.) and Jackie Speier (Calif.) and mayors from D.C., Newark and New York City rushed Twitter within the first hour of the interview to add their support to Obama's position and express their own opinions.

No Republicans rushed to tweet a reaction to the news, but GOProud, a leading Republican organization that supports LGBT rights, released a statement cautiously praising Obama’s announcement.

“This is hardly a profile in courage by President Obama. For years now, President Obama has tried his hardest to have it both ways on this issue,” co-founder Christopher R. Barron said in a statement. “The real kudos here goes to LGBT activists and their allies who finally forced the President into yielding on this issue.”

Similarly, the Log Cabin Republicans slammed Obama for failing to speak out earlier, particularly prior to the referendum vote by North Carolina the previous day when voters passed an amendment defining marriage as only between a man and a woman.

“Log Cabin Republicans appreciate that President Obama has finally come in line with leaders like Vice President Dick Cheney on this issue, but LGBT Americans are right to be angry that this calculated announcement comes too late to be of any use to the people of North Carolina, or any of the other states that have addressed this issue on his watch," said Executive Director R. Clarke Cooper in a statement. "This administration has manipulated LGBT families for political gain as much as anybody, and after his campaign’s ridiculous contortions to deny support for marriage equality this week he does not deserve praise for an announcement that comes a day late and a dollar short.”

—This post was updated at 3:35 and 3:58 p.m.