Biden: I wouldn't have agreed to replace Clinton in 2016

Former Vice President Joe BidenJoseph (Joe) Robinette BidenRasmussen poll: Nearly three-quarters of Dems want 'fresh face' as nominee in 2020 Biden: Trump, Putin presser was 'beneath the dignity' of the presidency Biden: I’m ‘ashamed’ of Trump’s border policies MORE said he would never have agreed to replace former Democratic presidential nominee Hillary ClintonHillary Diane Rodham ClintonOvernight Defense: Trump tries to quell Russia furor | GOP looks to reassure NATO | Mattis open to meeting Russian counterpart Dem pollster: GOP women have a more difficult time winning primary races than Dems Mellman: (Mis)interpreting elections MORE during the 2016 race.

During an interview on NBC's "Today," Biden was asked about former interim Democratic National Committee chairwoman Donna Brazile's comments that she considered replacing Clinton with Biden as the party's presidential nominee.

"Did anyone ever discuss that possibility with you? Would you have taken the nomination under those circumstances?" Biden was asked during the interview.

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Biden said the first time he heard about that possibility was in Brazile's book.

"I would never have taken it," Biden said. "I was for Hillary. I did 83 campaign events for Hillary. I think I can say I did more events and worked harder for Hillary, as hard for Hillary, as anyone else."

Biden said Clinton would have been a "first-rate president."

He said at that point, he had already made the judgment that he was "not prepared" to run for president.

"I was not ready, in terms of my family, so no, I would never have done that," he said.

In her book, “Hacks: The Inside Story of the Break-ins and Breakdowns That Put Donald TrumpDonald John TrumpTrump says he doesn't want to use 'adversary' to describe Russia Comey urges Americans to vote for Democrats in midterms Roby wins Alabama GOP runoff, overcoming blowback from Trump criticism MORE in the White House,” Brazile described concerns over Clinton's health during the campaign.

She wrote she considered removing Clinton and replacing her with Biden.

She ultimately decided against the shake-up, saying she felt she couldn't upend the campaign of the first woman presidential nominee of a major political party.

“I thought of Hillary, and all the women in the country who were so proud of and excited about her," she wrote. "I could not do this to them.”

In an interview earlier this month, Brazile said she didn't tell Biden he was her pick to replace Clinton if the party needed a "plan B."