The helicopter was conducting a night mission when it went down, according to the Associated Press. On Thursday, U.S. military officials in Afghanistan had yet to confirm any casualties as a result of the crash.
"Regrettably, we can confirm that four U.S. service members lost their lives in this crash," George Little, acting assistant secretary of defense for public affairs, told reporters at the Pentagon.
Pentagon spokesman Capt. John Kirby said Friday it was likely weather conditions that brought down the chopper.
"We still believe that weather was the principal cause [of the accident]," Kirby said."They're going to look at all factors, but right now it appears that weather was the principal cause."
He would not confirm if the U.S. soldiers aboard the Blackhawk were conducting a night raid, adding that no information is yet available on the mission.
While the Pentagon was not ruling out the possibility that the helicopter was taken down by enemy fire, defense officials are not aware of any enemy fire reported in the area where the crash took place, Kirby said.
He added that as with all such incidents, the crash remains under investigation until all possible details are determined.
News of the crash comes days after two Marines were killed in Southern Morocco when the V-22 Osprey they were in crashed.
Two other Marines were injured in the crash and transported to a military medical facility in Guelmim Province, about 450 miles south of Rabat.
The Marines were in Morocco for an annual joint U.S.-Moroccan military exercise called “African Lion.”
--This story was updated aw 1:23p.m. to include comments from Pentagon press secretary George Little and DoD spokesman Capt. John Kirby