Treasury Secretary Timothy Geithner does not anticipate serving a second term under President Obama.
Geithner said in an interview with Bloomberg Television that he is "pretty confident" the president would not ask him to stay on if he is reelected.
"I'm confident he'll be president. But I'm also confident he's going to have the privilege of having another secretary of the Treasury," he said, adding that he planned to do "something else."
"I love my work. And I think, if a president asks you to serve, you have to do it," he told NBC News in August.
The former head of the Federal Reserve Bank of New York played an integral part in steering the nation through the financial crisis that hit shortly before President Obama took office, and has served as a vocal advocate for the president's economic policies.
A key piece of that effort has been the Dodd-Frank financial reform law. Geithner said Wednesday he was not losing sleep over complaints from Wall Street that the overhaul is onerous and restrictive.
"I would not worry too much about them," he told Bloomberg. "I would worry more abut the basic confidence of Americans that they're going to face more opportunities, more likely to find a job, keep a job, save for college, save for a dignified retirement."