"We'll comply with all the issues when we know it is going to be the law of the land," he said. "If it's the law of the land, we're going to comply."
House Republicans are expected to hold a vote repealing whatever portions of the health law still stand in the immediate aftermath of a ruling. The effort will make little headway unless Republicans claim full control of Congress and the White House in November.
Before he was elected governor in 2010, Scott was already a prominent critic of "ObamaCare" as head of a group called Conservatives for Patients' Rights.
Florida now leads the group of states whose challenge is under consideration by the Supreme Court.
Scott noted that Florida has refused federal money associated with implementing portions of the law, including funds to set up the state's insurance exchange, because leaders are confident the law will be struck down.
He said if the law is upheld, he will "decide at the time" whether the state will move ahead to create its exchange or allow the federal government to do it.
"We'll have enough time," he said, adding, "if there is no obligation to do an exchange, Florida won't be doing an exchange."
Scott's call with reporters was sponsored by several conservative policy groups, including Grover Norquist's Americans for Tax Reform.
Florida Democratic Rep. Kathy Castor responded to the governor's comments later, saying that "nullification was rejected long ago."
"There has been no injunction, no stay" against the law, she said in a statement.
"[Scott] has acted in contravention to the law and cost Florida taxpayers dearly to the tune of more than $500 million … Consider how that money could have helped millions of Floridians," she said.
This post was updated at 1:03 p.m and 4:32 p.m.